Procite-D^TM

Use Procite-D™ to support the rebalancing process targeting dopamine/catecholamines.* 

The NeuroSupport Blend™ (NSB) is designed to enhance absorption, supporting the impact of ingredients.* 

As a potent excitatory formula, Procite-D may be recommendedin conjunction with additional formulas to create a comprehensive approach for the system picture that may arise on the path to wellness.

Mucuna pruriens (standardized to 20% L-DOPA) Natural source of L-DOPA, a direct precursor to the catecholamines dopamine, norepinephrine and epinephrine.*  

DL-Phenylalanine DL-phenylalanine acts a precursor to PEA as well as the catecholamine pathway.* 

N-Acetyl-L-Tyrosine Precursor to L-DOPA, the direct precursor to the catecholamines dopamine, norepinephrine and epinephrine.* 

N-Acetyl-L-Cysteine Antioxidant.* Helps maintain cell health during catecholamine supplementation.*¹

Folate (as (6S)-5-methyl-tetrahydro folic acid, glucosamine salt) (Quatrefolic®) Cofactor in methylation reactions essential for the synthesis of dopamine, norepinephrine and epinephrine.* 

Selenium Supports selenoproteins, important antioxidant enzymes.* Data shows reduced selenium activity can impact healthy dopamine, reducing activity. ²

Vitamin B6 (as pyridoxal-5’-phosphate) Active form of B6. Cofactor in the conversion of L-DOPA to dopamine.* 

Vitamin B12 (as Methylcobalamin) Coenzyme form of Vitamin B12.* Methyl donor.* 

NeuroSupport Blend™ (NSB) Proprietary mixture composed of Bioperine® and plant-based enzymes designed to maximize nutrient absorption.*

Serving Size: 1 Capsule
Servings Per Container: 60 Capsules

Procite-D™ Formula  435.75 mg  
Vitamin B6 (as pyridoxal-5-phosphate)
Folate (as (6S)-5-methyl-tetrahydro folic acid, glucosamine salt) (Quatrefolic®)
Vitamin B12 (as methylcobalamin)
Selenium (as L-selenomethionine)
N-Acetyl-L-Tyrosine
N-Acetyl-L-Cysteine
DL-Phenylalanine
Mucuna pruriens (std. to 20% l-Dopa) (seed)

NSB™ Proprietary Blend  102.5 mg
BioPerine® (Black Pepper Extract) (standardized to 95% piperine)(Piper nigrum) (fruit)
Protease
Amylase
Lipase

      
NSB™ is a trademark of Sanesco International Inc.

Quatrefolic® is a registered trademark of Gnosis S.p.A, U.S. Patent No. 7,947,662

BioPerine® is a registered trademark and a product of Sabinsa Corp.

Dopamine balance is important to maintain: 

• Motivation^3,4
  
• Balanced impulse control^5,6
  
• Cravings, healthy pleasure/reward feelings^7-10
  
• Healthy libido^11-14

Norepinephrine balance is important to maintain: 

• Healthy stress response^15-17
  
• Healthy mood
• ^{Temperature balance18-20}
• ^{Balanced energy21}
• Healthy focus and cognitive function^22,23
  
• Healthy bodily comfort^24,25

Epinephrine balance is important to maintain: 

• Healthy tress response^15,16,27
  
• Balanced emotional health²⁸
  
• Healthy blood sugar maintenance^16,29
  
• Weight management balance^27,31,32
  

PEA balance is important to maintain: 

• Mental and emotional health balance^32,33
  
• Healthy focus^{33, 34}

1. Noh J, Kim E, Kang J, et al. Experimental Neurology. 159, 217–224. 
2. Gashu, D and Stoecker BJ. Selenium and Cognition: Mechanism and Evidence. In: Preedy V., Patel V. (eds) Handbook of Famine, Starvation, and Nutrient Deprivation. Springer, Cham 2017:1-17. Accessed on August 6, 2019 https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-40007-5_21-2 
3. Palmiter RD. Ann N Y Acad Sci. 2008;1129:35-46.
4. Felger JC and Treadway MT. Neuropsychopharmacology. 2017 Jan;42(1):216-241.
5. Kelley BJ, et al. Parkinsons Dis. 2012;2012:603631.
6. Athanasoulia-Kaspar AP, et al. Endocr Connect. 2018 Feb;7(2):R88-R94.
7. Blum K, et al. Curr Neuropharmacol. 2017;15(1):184-194.
8. Burger KS and Stice E. Am J Clin Nutr. 2012 Apr;95(4):810-7.
9. Stice E, et al. J Neurosci. 2010 Sep 29;30(39):13105-9.
10. Lennerz B and Lennerz JK. Clin Chem. 2018 Jan;64(1):64-71.
11. Abler B, et al. Neuropsychopharmacology. 2011 Aug;36(9):1837-47.
12. Goldstein I, et al. Mao Clin Proc. 2017 Jan;92(1):114-128.
13. Just MJ. Neuropsychiatr. Dis Treat. 2015 Jul 8;11:1655-61.
14. Stahl SM. J Clin Psychiatry. 2010 Jul;71(7):821-2.
15. Lieberman HR, et al. Physiol Behav. 2016 Oct 15;165:86-97.
16. Wong H, et al. Cureus. 2019 Aug 24;11(8):e5474.
17. Flak JN, et al. Eur J NeuroSci. 2014 Jun;39(11):1903-11.
18. Bansal R and Aggarwal N. J Midlife Health. 2019 Jan-Mar;10(1):6-13.
19. Freedman RR. Fertil Steril. 1998 Aug;70(2):332-7.
20. Gordon JL, et al. Menopause. 2016 Nov;23(11):1189-1198. 
21. Brennan AR and Arnsten AF. Ann N Y Acad Sci. 2008;1129:236-45.
22. Arnsten AF and Pliszka SR. Pharmacol Biochem Behav. 2011 Aug;99(2):211-6. 
23. Borodovitsyna O, et al. Neural Plast. 2017;2017:6031478. 
24. Ho KY, et al. Br J Anaesth. 2010 Sep;105(3):371-6.
25. Hoshino H, et al. Anesth Analg. 2015 Feb;120(2):460-6.
26. Lee ZS, et al. Metabolism. 2001 Feb;50(2):135-43.
27. Rief W, et al. Psychosom Med. 2010 Oct;72(8):755-62.
28. Paine NJ, et al. Psychosom Med. 2015 Feb-Mar;77(2):136-44.
29. Howlett K, et al. J Physiol. 1999 Sep 15;519 Pt 3:911-21.
30. Corbi GM, et al. J Clin Endocrinol Metab. 2002 May;87(5):2080-3.
31. Couillard C, et al. Obes. Res. 2002 Jan;10(1):6-13.
32. Szabo A, et al. Br J Sports Med. 2001 Oct;35(5):342-3.
33. Kaur N and Kumari B. World J Pharm & Pharmaceut Sci. 2016 Mar;5(4):743-750.
34. Irsfeld M, et al. Webmedcentral. 2013 Sep 30;4(9). pii: 4409.